Figure 2. Different sugars affect the expression of RAMP3, TRH and CRH in the PVN, VMH and LH. (A-C) Both HFCS and fructose significantly decreased RAMP3 mRNA expression compared with glucose in the VMH. In the LH RAMP3 expression was only significantly reduced in the HFCS group when compared to the glucose group (D-F) Both fructose and HFCS reduced TRH mRNA expression when compared with sucrose in the PVN. No other differences were found in the VMH or LH. (G-I) No significant difference in CRH was found in the PVN, VMH or LH

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Overnight Access to Sugar Solutions Affects mRNA Expression of Several Neuropeptides in Different Hypothalamic Regions in Rats

Changhui Zhao, Eric S. Campbell, Anna E. Tschiffely, Thomas W. Castonguay

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