Figure 4. ZLE decreased the lipid levels in a dose-dependent manner. The triglyceride and cholesterol levels in HepG2 cells were measured with a Colorimetric/Fluorometric Kit; Results are representative of 3 independent experiments (n=3), *p < 0.05 vs FFAs group. The effect of ZLE on serum lipids in apoE-/- mice were showed in Fig 4 Ⅱ. Group A: Control group, use 0.5% CMC; Group B: Model group given 0.5% CMC fed with a high diet. Group C: ZLE group given a dosage of 250 mg/(kg.d); and Group D are positive group given a dosage of fenofibrate (100 mg/kg.d). The experiment last 2 months, lipid levels in model group were significantly higher than those in the control group, and treatment with ZLE (250 mg/kg.d) had great effect on the level of lipids compared with fenofibrate. *p < 0.05 vs Control group; # p < 0.05 vs Model group


High Anti-oxidative and Lipid-lowering Activities of Flavonoid Glycosides-rich Extract from the Leaves of Zanthoxylum bungeanum in Multi-system

Limei Ma, Ke Li, Dandan Wei, Hengyi Xiao, Hai Niu, Wen Huang

Journal of Food and Nutrition Research. 2015, 3(1), 62-68 doi:10.12691/jfnr-3-1-11