Table 2c. Serum levels of total thiols (mmol/L), glutathione (GSH) (μg/mL), catalase (IU/L), superoxide dismutase (SOD) (U/mL), glutathione peroxidase (GSH-Px) (U/mL), and total antioxidant capacity (TAC) (nmol/mL), malondialdehyde (MDA) (nmol/mL), hydrogen peroxide (H2O2) (mmol/L), and total antioxidant capacity (TAC) (nmol/mL) in the different groups. Compared to the untreated control rats, the cadmium-exposed rats exhibited significantly decreased levels of total thiols, GSH, catalase, and TAC. The levels of malondialdehyde (MDA) and hydrogen peroxide (H2O2) were significantly increased in cadmium-exposed rats compared to the untreated control rats. Rosmarinic acid-treated rats showed no significant differences in the measured biochemical parameters compared to the untreated control rats. In the rats exposed to cadmium and treated with rosmarinic acid, the biochemical parameters showed improvements toward the control levels and were significantly different compared to those of the cadmium-exposed rats

From

Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity

Mohammed Al-Zharani, Eman Almuqri, Mohammed Mubarak, Hassan Rudayni, Nada Aljarba, Khadijah Yaseen, Shaikha A. Albatli, Saad Alkahtani, Fahd A. Nasr, Amin A. Al-Doaiss, Mohammed S. Al-eissa

Journal of Food and Nutrition Research. 2024, 12(11), 528-536 doi:10.12691/jfnr-12-11-9