Figure 4. The effects of SFN on the expression of anti-oxidant or pro-inflammatory genes in LPS-stimulated mouse BMDMs. Cells were preincubated with SFN for 1 hour and co-treated with LPS for 12 hours. (A & B) Gene expression by RT-PCR. # P<0.05, ## P<0.01, ### P<0.001 as compared to control (unstimulated cells), * P<0.05, ** P<0.01, *** P<0.001 as compared to only LPS-stimulated cell. Ψ P<0.05, ΨΨ P<0.01, ΨΨΨ P<0.001 as compared to SFN at 10 μM. n = 3, bars represent mean ± S.D

From

Sulforaphane (SFN) Exerts Anti-inflammatory Effects on LPS-stimulated RAW 264.7 and Mouse Bone Marrow Driven Macrophages by Modulating p65 Phosphorylation and Histone Acetylation

Seok-Yeong Yu, Zhenhua Liu, Soonkyu Chung, Young-Cheul Kim

Journal of Food and Nutrition Research. 2023, 11(3), 269-276 doi:10.12691/jfnr-11-3-12