Figure 8. Representation of multiple pathways used by anti-cancer drugs such as tamoxifen and analogues, histone deacetylase inhibitors (HDACI/SBHA) to regulate cell proliferation, induce apoptosis or cell differentiation. Pathways A, B and C were documented [1,8,9,10]. Our study suggested that SBHA may use pathway D in presence of lamin A to inhibit breast cancer cell growth

From

Presence of Lamin A is Required for GATA3 and ERα Downregulation by Histone Deacetylase Inhibitor in Breast Cancer Cells

Callinice D. Capo-chichi, Freddy Gnangnon, Charles Mekpossi, Sara Houngue, Xiang-Xi Xu, Jean-Leon Olory-Togbé

Journal of Cancer Research and Treatment. 2018, 6(3), 60-69 doi:10.12691/jcrt-6-3-1