Figure 4. Microscopy images showing the effect of Histone deacetylase inhibitor SBHA on MCF7 cells. This effect is dose dependent: (A) MCF7 control treated with DMSO (mock) for 12h compared to MCF7 treated for 12 h with (B) 0.5 µM SBHA; (C) 1 µM SBHA and (D) 2 µM SBHA. Apoptosis (rounded cells) is induced in a dose dependent manner

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Presence of Lamin A is Required for GATA3 and ERα Downregulation by Histone Deacetylase Inhibitor in Breast Cancer Cells

Callinice D. Capo-chichi, Freddy Gnangnon, Charles Mekpossi, Sara Houngue, Xiang-Xi Xu, Jean-Leon Olory-Togbé

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