Figure 2. Percentage of metaphases in MCF7 cells stably transfected with histone H2B-GFP, Lamin A-RFP, or Lamin C-GFP. MCF7 proliferation is significantly reduced in presence of lamin A-RFP (4.4%) or lamin C-GFP (3.6%) in contrast to the control transfected with PCDNA3-H2B-GFP (22%)

From

Presence of Lamin A is Required for GATA3 and ERα Downregulation by Histone Deacetylase Inhibitor in Breast Cancer Cells

Callinice D. Capo-chichi, Freddy Gnangnon, Charles Mekpossi, Sara Houngue, Xiang-Xi Xu, Jean-Leon Olory-Togbé

Journal of Cancer Research and Treatment. 2018, 6(3), 60-69 doi:10.12691/jcrt-6-3-1