Figure 3. Effects of PL-fractions on G₁ cell cycle regulators. 5637 cells were treated with PL-I (400 µg/ml), PL-II (300 µg/ml), or PL-III (50 µg/ml) for 72 h. The expressions of four G₁ cell cycle regulators, CDK2, CDK4, p21^WAF1, and p27^Kip1, were analyzed by Western blots. Although exactly the same expression patterns of these four regulators were observed with treatment of all three fractions, only autoradiographs of four regulators seen with PL-III are shown here. Additionally, β-actin is shown as a protein loading control

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Alternative Therapeutic Approach to Urothelial Cell Carcinoma with Medicinal Mushroom Extracts

Amul Bhalodi, Mark Ferretti, Matthew Chaimowitz, Muhammad Choudhury, John Phillips, Sensuke Konno

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