Figure 2. Various mechanisms of theaction of immunomodulatory drugs (IMiDs). IMiDs have multiple effects including immunomodulatory activity, anti-angiogenic activity, intervention of cell surface adhesion molecules, cell cycle arrest, inhibition of cell migration and metastasis, anti-proliferation aktivity, anti-inflammatory aktivity, and pro-apoptotic activity

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Cereblon and Its Role in the Treatment of Multiple Myeloma by Lenalidomide or Pomalidomide

Ota Fuchs, Radka Bokorová, Martin Vostrý, Arnošt Kostečka, Jaroslav Polák

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