Figure 1. Enterocytes are not positioned along the basement membrane in a linear fashion, as illustrated in the upper display. Therefore, counts of 'enterocytes' (lower diagram) cannot be accomplished as easily as some Methods Sections, as reported in many papers, might suggest. This model obviously predicts that it would be possible to observe large tracts of enterocytes without their nuclei. But that is never encountered in practice. Nevertheless, one could be tempted, while working at the microscope, to think that adjacent nuclei meant that strips of adjacent enterocytes were always being counted. That conceptualisation would likewise be wrong

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It's Counting That Counts

Michael N Marsh

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