Figure 3. FACS analysis of isolated IELs from duodenal mucosabiopsies. Forward andsidewardscatter (FSC, SSC) wereusedtogateforlymphocytes. CD103⁺, surCD3^-cellsweregatedandanalyzedfor CD7 and cytoplasmic-CD3 expression. Upperpanel: duodenal mucosaof a patientwith RCD type II (61% aberrant IELs). Middlepanel: Same patient after treatmentwirthcladribine (3% aberrant IELs). Lowerpanel: Duodenal mucosaof a healthy individual (8% aberrant IELs)

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Refractory Celiac Disease New Diagnostic Approaches and Current Treatment

Michael Schumann, Christian Bojarski, Verena Moos, Severin Daum

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