Open Access Peer-reviewed

A Model Considering Secondary Particles Contribution in RBE of Primary Bremsstrahlung

Alexandr V. Belousov1,, Alexandr P. Chernyaev1, Alexey S. Osipov1

1Physics Department, Lomonosov Moscow State University, Moscow, Russia

Biomedicine and Biotechnology. 2013, 1(2), 6-8. DOI: 10.12691/bb-1-2-1
Published online: August 25, 2017

Abstract

Passage of ionizing radiation through biological matter, for example during beam therapy, is followed by the production of secondary particles, which change the relative biological effectiveness (RBE) of the beam. The absorbed dose is represented by the sum of two components: the dose delivered by photons and secondary e+ and e- and the dose from heavy charged particles. Therefore, in order to assess the overall biological effectiveness of the beam, it is necessary to consider RBE of all kinds of induced radiation. In this work a model theoretically describing the biological effectiveness of various types of ionizing radiation depending on their energies is proposed. A method for estimating the relative biological effectiveness taking into account the contribution of photonuclear reactions with the energy ranging from a threshold of photonuclear reactions on light elements (Z<10) to 50MeV is developed. The results obtained are compared to the experimental and calculated data of the other authors.

Keywords:

bremsstrahlung, relative biological effectiveness, photonuclear particles
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