Figure 7. Escitaloprams lodged in the central and allosteric site of the SERT. The green coloured escitalopram is in the allosteric site while the red coloured escitalopram is embedded in the central site and both citaloprams are separated by the extracellular gate

From

Molecular Docking and In-Silico ADME Prediction of Substituted (E)-4-Styryl-7,8-dihydroquinazolin-5(6H)-ones and 5-((E)-Styryl)pyrimidine[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potential SERT Inhibitors and Antidepressants

Oyesakin Y.M., George D.E., Fadare R.Y., Idris A.Y., Fadare O.A.

American Journal of Pharmacological Sciences. 2018, 6(1), 25-32 doi:10.12691/ajps-6-1-5