Table 2. Table of predicted ADME properties for some selected compounds, showing values for BBB penetration, P-gp association, human intestinal absorption, plasma protein binding and CYP 450 enzymes associations as a measure of hepatic metabolism

From

Molecular Docking and In-Silico ADME Prediction of Substituted (E)-4-Styryl-7,8-dihydroquinazolin-5(6H)-ones and 5-((E)-Styryl)pyrimidine[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potential SERT Inhibitors and Antidepressants

Oyesakin Y.M., George D.E., Fadare R.Y., Idris A.Y., Fadare O.A.

American Journal of Pharmacological Sciences. 2018, 6(1), 25-32 doi:10.12691/ajps-6-1-5