Acute appendicitis is commonest cause of acute abdomen necessitating emergency abdominal surgery. Although diagnosis is still largely considered to be a clinical one, ultrasound is established as easily available, less time consuming and very accurate at timely diagnosis of acute appendicitis largely reducing complications as well as negative laparotomies. Due to development of high frequency transducers and better resolution, ultrasound is highly specific and sensitive in diagnosis of acute appendicitis. This study was done to establish the diagnostic role of ultrasound in acute appendicitis in western region of Nepal. Total number of 125 patients were included in the study from May 2013 to May 2015. Findings on ultrasound were finally compared with histopathological report of appendices removed on surgery. Those cases with alternate diagnosis were followed up and proved with other means of investigation. The sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy of ultrasound in diagnosis of acute appendicitis in our study were found to be 95.12 %, 88.88 %, 97.5% , 80% and 82 % respectively.
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