This study investigated how stress-related and demographic factors predict mental health challenges among postgraduate students at Makerere University, Uganda. A cross-sectional survey of 391 Master’s and Ph.D. students was analyzed using binary logistic regression. Significant predictors of mental health challenges included female gender, certain marital statuses, non–full-time employment, financial stress affecting academic performance, limited support systems, infrequent exercise, strained student–supervisor relationships, maladaptive coping strategies, perceived social isolation, and dissatisfaction with supervision. The model explained 73.3% of the variance in outcomes (Cox & Snell R² = .733). Findings emphasize the multifaceted interplay of academic, financial, relational, and psychosocial stressors contributing to psychological distress among postgraduate students. The results support the need for targeted institutional interventions in academic advising, financial assistance, mental health services, and peer/social support.
| [1] | Mousavi, M. P. S., Sohrabpour, Z., Anderson, E. L., Stemig-Vindedahl, A., Golden, D., Christenson, G., Lust, K., & Bühlmann, P. (2018). Stress and Mental Health in Graduate School: How Student Empowerment Creates Lasting Change. Journal of Chemical Education, 95(11), 1939-1946.View Article |
| [2] | Milicev, J., McCann, M., Simpson, S. A., Biello, S. M., & Gardani, M. (2023). Evaluating Mental Health and Wellbeing of Postgraduate Researchers: Prevalence and Contributing Factors. Current Psychology, 42(14), 12267-12280.View Article |
| [3] | Uganda, U. S. M. (2024, June 6). U.S. Government Invests in Ugandans’ Mental Health | June 6, 2024. U.S. Embassy in Uganda. https://ug.usembassy.gov/u-s-government-invests-in-ugandans-mental-health-june-6-2024/. |
| [4] | Fiest, K. M., Jette, N., Quan, H., St. Germaine-Smith, C., Metcalfe, A., Patten, S. B., & Beck, C. A. (2014). Systematic review and assessment of validated case definitions for depression in administrative data. BMC Psychiatry, 14(1), 289.View Article PubMed |
| [5] | Depressive disorder (depression). (n.d.). Retrieved June 10, 2025, from https://www.who.int/news-room/fact-sheets/detail/depression |
| [6] | Hosseinpur, H., Parsa, A. D., & Kabir, R. (2023). The Prevalence of Depression and its Predictors among International Postgraduate Students Studying Public Health at a UK University. Journal of Psychosexual Health, 5(2), 94-101.View Article |
| [7] | Byrom, N. C., Dinu, L., Kirkman, A., & Hughes, G. (2022). Predicting stress and mental wellbeing among doctoral researchers. Journal of Mental Health, 31(6), 783-791.View Article PubMed |
| [8] | Berry, C., Niven, J. E., & Hazell, C. M. (2021). Personal, social, and relational predictors of UK postgraduate researcher mental health problems. BJPsych Open, 7(6), e205.View Article PubMed |
| [9] | Caesens, G., Stinglhamber, F., & Luypaert, G. (2014). The impact of work engagement and workaholism on well-being: The role of work-related social support. Career Development International, 19(7), 813-835.View Article |
| [10] | Sokratous, S., Alexandrou, G., Zavrou, R., & Karanikola, M. (2023). Mental health status and stressful life events among postgraduate nursing students in Cyprus: A cross-sectional descriptive correlational study. BMC Nursing, 22(1), 294.View Article |
| [11] | Mackie, S. A., & Bates, G. W. (2019). Contribution of the doctoral education environment to PhD candidates’ mental health problems: A scoping review. Higher Education Research & Development, 38(3), 565–578.View Article |
| [12] | Ferrari, F., & Villa, R. F. (2017). The Neurobiology of Depression: An Integrated Overview from Biological Theories to Clinical Evidence. Molecular Neurobiology, 54(7), 4847-4865.View Article PubMed |
| [13] | Barchas, J. D., & Altemus, M. (1999). Monoamine Hypotheses of Mood Disorders. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition. Lippincott-Raven. https://www.ncbi.nlm.nih.gov/books/NBK28257/. |
| [14] | Hypothalamic Pituitary Adrenal (HPA) Axis in Depression. (n.d.). Neurotorium. Retrieved June 10, 2025, from https:// neurotorium.org/ image/ hypothalamic-pituitary-adrenal-hpa-axis-in-depression-2/. |
| [15] | Berk, M., Williams, L. J., Jacka, F. N., O’Neil, A., Pasco, J. A., Moylan, S., Allen, N. B., Stuart, A. L., Hayley, A. C., Byrne, M. L., & Maes, M. (2013). So depression is an inflammatory disease, but where does the inflammation come from? BMC Medicine, 11(1), 200.View Article PubMed |