Abstract

Introduction: Cardiac disorders remain a major global health challenge, contributing to high morbidity, mortality, and reduced quality of life [QoL]. Beyond physical symptoms, these conditions affect psychological and social well-being. Nurse-led intervention programs have emerged as a key approach in cardiac care, providing education, psychosocial support, and structured follow-up to empower patients and improve outcomes. Materials and methods: A narrative review was conducted using PubMed, CINAHL, and PsycINFO databases, focusing on studies published between 2015 and 2025. Randomized controlled trials, cohort studies, and qualitative studies were included if they examined nurse-led interventions and their impact on QoL in cardiac populations. Eligible studies 17 were thematically synthesized into ten core domains: education, medication adherence, lifestyle modification, psychosocial support, self-care empowerment, healthcare resource use, long-term outcomes, disparities in access, patient perspectives, and interdisciplinary collaboration. Results: Nurse-led programs improved patient knowledge, self-care skills, and medication adherence, leading to fewer hospital readmissions and better symptom management . Lifestyle modifications guided by nurses enhanced vitality and reduced cardiovascular risk . Psychosocial support decreased anxiety and depression, strengthening coping strategies . Evidence also supported cost-effectiveness and healthcare savings . However, challenges included heterogeneous program design, sustainability concerns, digital inequities, and nurse workforce burden . Patient satisfaction was consistently high, correlating with improved perceived QoL . Interdisciplinary collaboration amplified benefits but required clear role delineation and communication pathways . Conclusion: Nurse-led interventions play a vital role in improving QoL among patients with cardiac disorders by addressing clinical, behavioral, and psychosocial needs. Despite clear benefits, barriers to sustainability and equity must be overcome. Future research should emphasize long-term effectiveness, scalable models, and workforce sustainability to strengthen nurse-led care as a cornerstone of cardiac management.