Figure 13. The equilibria for the 1:1 complex formed between 4-fluorophenol and 2,2-dichloropropane. Here the donor can either bind to the red chlorine or the blue chlorine

From

It Is Important to Compute Intramolecular Hydrogen Bonding in Drug Design?

María J. R. Yunta

American Journal of Modeling and Optimization. 2017, 5(1), 24-57 doi:10.12691/ajmo-5-1-3