Figure 2. A, B, C. Atypical Choroid Plexus Papilloma (10x, 20x, 40x magnification). Papillary neoplasm composed of papillary fronds, lined by single to multiple layers of cuboidal epithelium, with fibrovascular cores. Neoplasm showed increased cellularity, mild nuclear pleomorphism and increased mitosis (11/10 HPFs) (C- black arrow-mitotic figure). No blurring of architecture, sheets of neoplastic cells or necrosis was seen. D. Vimentin, immunohistochemical stain, showed positive staining of the neoplastic cells (20x magnification). E. Cytokeratin Cam 5.2 immunohistochemical stain showed positive staining in the neoplastic cells (20x magnification). F. P53 immunohistochemical stain was negative in the neoplastic cells (20x magnification). Other positive immunohistochemical stains included: AE1/AE3, CK7, S100 and E-cadherin, and negative immunohistochemical stains included: GFAP, CEA and TTF-1. Ki-67 proliferation index was around 15-20%

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Atypical Choroid Plexus Papilloma an Uncommon Entity: A Case Report

G P Mishra, Neeraj Salhotra, Simin Laiq, Zahra Al Hajri, Jospaul Lukas, Samit Biniwale, Ahmed Tolba, Faraz Qayyum Khan

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