Figure 4. Predominant GI disease and feco- Oral transmission of covid-19 infection (A, Delayed, and weak Innate immune response due to lack of type I interferon response, decreased antigen presentation by dendritic cells, decreased NK cell lethality caused by viral structural and nonstructural protein interference. B, Adaptive immune response compromised by the overwhelming viral presence, especially in feco-oral transmission. Weak "mishit" cytokine response inept in viral clearance but causes inadvertent mucosal injury and cell death.)

From

Gastrointestinal Symptoms and Immune Response in COVID 19 - Review of a Cat and Mouse Game Theory

Abhilash Haridas, Payal Mukker

American Journal of Medical Case Reports. 2021, 9(1), 24-31 doi:10.12691/ajmcr-9-1-8