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Carcinoma Breast Male: A Case Report
Sujit K Prasad1, Anuj Kumar Srivastava2,
1Consultant Surgeon, MGM Hospitals, Navi Mumbai, India
2Additional professor, Department of surgery, SSR Medical College, Mauritius
Abstract
Carcinoma of male breast is a rare cancer in male and accounts for less than 1% of all breast cancers. Affected men are usually in their 7th or 8th decade. In a study in India 0.7% of breast carcinoma is seen in men. Predisposing factors include genetic factors, exposure to radiation and excess estrogen. High exposure to estrogen may result from excess estrogen conditions or due to androgen deficiency states.
At a glance: Figures
Keywords: carcinoma, male breast, estrogen excess states, mastectomy
American Journal of Medical Case Reports, 2014 2 (3),
pp 48-49.
DOI: 10.12691/ajmcr-2-3-1
Received November 20, 2013; Revised March 05, 2014; Accepted March 18, 2014
Copyright © 2013 Science and Education Publishing. All Rights Reserved.Cite this article:
- Prasad, Sujit K, and Anuj Kumar Srivastava. "Carcinoma Breast Male: A Case Report." American Journal of Medical Case Reports 2.3 (2014): 48-49.
- Prasad, S. K. , & Srivastava, A. K. (2014). Carcinoma Breast Male: A Case Report. American Journal of Medical Case Reports, 2(3), 48-49.
- Prasad, Sujit K, and Anuj Kumar Srivastava. "Carcinoma Breast Male: A Case Report." American Journal of Medical Case Reports 2, no. 3 (2014): 48-49.
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1. Introduction
The affected male with carcinoma breast is usually in his sixties of seventies. Histological types and routes of metastasis(lymphatics and vascular) of male breast cancer are similar as in females. Hence the TNM staging system of male breast carcinoma is same as in females. Excess estrogen exposure is a common cause and may result from excess estrogen levels or due to deficient states. Genetic mutation, obesity, alcoholism, liver disease, senescence are important predisposing factors. Men with BRCA1, BRCA2 and Klinefelter’s syndrome are at highest risk of developing breast cancer. Size of the tumour and lymph node status are prognostic determinants.
2. Case Report
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A 65 year old male presented with “deformity of the right side of chest” On examination, the nipple retraction was apparent but there was no nipple discharge. A firm retroareolar mass of size 3 X 3 cm (approx.) was palpable. There were no clinically palpable axillary lymph nodes. The left breast and axilla were normal. FNAC of right breast lesion was done which depicted ductal epithelial carcinoma. Modified radical mastectomy with axillary clearance was done on priority. Patient is now on Tamoxifen which we intend to continue for 5 years.
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Larger image(png format)3. Discussion
Male breast cancer has identical pathology as in females, but lesions infiltrate locally faster due to lesser breast tissue. In 50% of cases, lesion in male is in advanced stageIII. Hence the treatment guidelines are based on experience in female breast cancer management doing mastectomy initially followed by relevant adjuvant therapy.
References
| [1] | Schottenfeld D, Lilienfeld AM, Diamond H (1963); Some observations on epidemiology of breast cancer among males, American journal of public health 53, 890897. | ||
 In article | |||
| [2] | Donegan WL (1991) Cancer of breast in men, CA-A journal of clinicians 41, 339354. | ||
| In article | |||
| [3] | Sosco AJ, Lowenfel AB, Pasker de jong P (1993) Epidemiology of male breast cancer, International Journal of Cancer 53, 538549. | ||
| In article | |||
| [4] | Stromm HH,Olson J (1999) Risk of breast cancer in offspring of male breast cancer patient, Lancet 353, 209. | ||
| In article | CrossRef | ||
| [5] | Johansen Taber KA et al, Male breast cancer; Risk factors, diagnosis, management; Oncology Reports2010; 24; 1115. | ||
| In article | CrossRef | ||
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