Figure 5. Depictive comparative assessment of the antimicrobial efficacy of various detergents against gram-positive Streptococcus Group A (S. pyogenes) bacteria, as compared with novobiocin (30 μg). The zone of inhibition of novobiocin was set as a reference (lane 24; horizontal straight line), and that for absolute methanol (MetOH) is shown in lane 23, and all values of the zones of inhibition at undiluted concentrations of disinfectant/sterilizer/antiseptic were compared against those references (Lanes 23 and 24). Lanes 1 – 5 represent Class A (Daily Mouthwash); Lanes 6 – 14 represent Class B (Toilet Bowl Cleaners/Bleaches/Sanitizers); Lanes 15 – 19 represent Class C (Surface and Floor Mopping Cleaners/Detergents); and Lanes 20 – 22 represent Class D (Hand and Body Wash Gels). This comparative analysis allows descriptive visualization of the antimicrobial effectiveness relative to novobiocin, on one hand, and various classes (A – D), on the other hand, thereby showing the most effective class and/or detergent within a given category against a specific type of bacteria. The number of experimental observations is n = 3, * P< 0.05, ** P< 0.01, *** P< 0.001, as compared with either novobiocin or absolute MetOH. NI = No inhibition.

From

The Immunomodulatory, Antimicrobial and Bactericidal Efficacy of Commonly Used Commercial Household Disinfectants, Sterilizers and Antiseptics in Vitro: Putative Anti-Inflammatory Infection Control Mechanisms and Comparative Biochemical Analysis of the Microbial Growth of Gram-Positive Bacteria

Niveen M. Masri, Lama B. Hanbali, Ahmad H. Kamar, Lana M.S. Kanafani, Mohamed B. Hanbali, John J. Haddad

American Journal of Medical and Biological Research. 2013, 1(4), 103-133 doi:10.12691/ajmbr-1-4-4