Figure β. Phylogenetic analysis and homology modeling of the Receptor-binding domain of the 2019-nCoV, SARS-CoV, and MERS-CoV. (A) Phylogenetic analysis of the receptor-binding domain from various betacoronaviruses. The star highlights 2019-nCoV and the question marks means that the receptor used by the viruses remains unknown. Structural comparison of the receptor- binding domain of SARS-CoV (B), 2019-nCoV (C), and MERS-CoV (D) binding to their own receptors. Core subdomains are magenta, and the external subdomains of SARS-CoV, 2019-nCoV, and MERS CoV are orange, dark blue, and green, respec- tively. Variable residues between SARS-CoV and 2019-nCoV in the receptor-binding site are highlighted as sticks. CoV= coronavirus. 2019-nCoV=2019 novel coronavirus. SARS-CoV=severe acute respiratory syndrome coronavirus. MERS= Middle East respiratory syndrome coronavirus [9]

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Analysis on the Dynamic Attributes of SARS-CoV-2 and COVID-19

Mohd Abass Dar, Garima Charak, Suman Bala, Sudhanshu Shekhar, Muneeb Qadir

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