Open Access Peer-reviewed

Main Points of Coronary Artery Disease in Chronic Kidney Disease

Kultigin Turkmen1,, Emin Murat AKBAS2, Fatih Ozcicek3, Aysu Ozbicer3, Levent Demirtas3, Adalet Ozcicek3, Ilyas Capoglu2

1Division of Nephrology, Department of Internal Medicine, Mengücek Gazi Training and Research Hospital, Erzincan University, Erzincan, Turkey

2Division of Endocrinology and Metabolism, Department of Internal Medicine, Mengücek Gazi Training and Research Hospital, Erzincan University, Erzincan, Turkey

3Department of Internal Medicine, Mengücek Gazi Training and Research Hospital, Erzincan University, Erzincan, Turkey

American Journal of Hypertension Research. 2013, 1(1), 1-5. DOI: 10.12691/ajhr-1-1-1
Published online: August 25, 2017

Abstract

Cardiovascular diseases are the most common cause of mortality and morbidity in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) receiving hemodialysis and peritoneal dialysis. Beside traditional risk factors including hypertension, diabetes, dyslipidemia, advanced age novel risk factors such as endothelial dysfunction, hyperphosphatemia, hyperparathyroidism, vascular calcification, increased oxidative stress and inflammation are highly prevalent and seem to play a more important role for vascular disease in CKD and ESRD patients compared to general population. This review briefly discuss classical and recent epidemiologic, pathophysiologic and clinical aspects of coronary artery disease in ESRD patients.

Keywords:

chronic kidney disease (CKD), cardiovascular disease (CVD), atherosclerosis
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