Figure 2. Effects of Notch1 knock down in MCF-7 cells on H4K16ac expression level. MCF-7 cells were transfected with Notch1 specific si-RNA, si-RNA negative control or LipofectamineTM2000 reagent without any si-RNA. Then real-time quantitative RT-PCR was done to quantify mRNA expression of Notch1 (A) and western blot was done to quantify protein expression of Notch1 (B) (C)

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Histone Acetylation Modification H4K16ac Involved in Notch1 Signaling in Breast Cancer

Ya-qi Wang, Jing-hua Zhang, Zhao-yuan Wan, Dan Li

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