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Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis after the Allogeneic Stem Cell Transplantation-A Case Report

Mehrdad Payandeh1, Sakineh Ghorbani2, Afshin Karami3, Neda Veisi4,, Ali Ghasemi4, Mohammad Mehdi Maadikhah4, Mojtaba Gorji5, Mehrnoush Aeinfar1, Fatemeh Yari2, Masomeh Farhadi2

1Department of Hematology and Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Medical Bone Marrow Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

3Department of Hematology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4Kermanshah University of Medical Sciences, Kermanshah, Iran

5Department of Hematology and Oncology, Lorestan University of Medical Sciences, School of Medicine, Khorramabad, Iran

American Journal of Cancer Prevention. 2018, 6(2), 32-34. DOI: 10.12691/ajcp-6-2-4
Published online: June 05, 2018

Abstract

Hemorrhagic cystitis (HC) is a significant clinical problem that occurs after allogeneic transplantation and is often refractory. The patient was a 40-year-old man who had HC after two months of transplantation of allogeneic stem cells. Several treatments were used to improve the patient, but no improvement. At the doctor's proposal, 5 sessions of Ozone therapy were performed for the patient, After the completion of the sessions, the clinical symptoms associated with HC disappeared completely. This study shows that HC treatment with ozone therapy is an effective and tolerable method and does not have any clinical complications.

Keywords:

hyperbaric oxygen therapy, hemorrhagic cystitis, allogeneic, transplantation
[1]  Tsuboi K, Kishi K, Ohmachi K, Yasuda Y, Shimizu T, Inoue H, et al. Multivariate analysis of risk factors for hemorrhagic cystitis after hematopoietic stem cell transplantation. Bone marrow transplantation. 2003; 32(9): 903.View Article  PubMed 
 
[2]  Decker DB, Karam JA, Wilcox DT. Pediatric hemorrhagic cystitis. Journal of pediatric urology. 2009; 5(4): 254-64.View Article  PubMed 
 
[3]  Demesmay K, Tissot E, Bulabois C-E, Bertrand M-A, Racadot E, Woronoff-Lemsi M-C, et al. Factor XIII replacement in stem-cell transplant recipients with severe hemorrhagic cystitis: a report of four cases. Transplantation. 2002; 74(8): 1190-2.View Article  PubMed 
 
[4]  de Gracia SR, Bento L, Gutiérrez A, Mañó LG, Novo A, Sampol A. The Use of Hyperbaric Oxygen Therapy for Refractory Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 2016; 22(3): S354.View Article 
 
[5]  Urbaniak-Kujda D, Kapelko-Słowik K, Biernat M, Dybko J, Laszkowska M, Kuliczkowski K. The use of hyperbaric oxygen therapy in the treatment of hemorrhagic cystitis after allogeneic stem cell transplantation from an unrelated donor. International journal of hematology. 2015; 102(3): 364-7.View Article  PubMed 
 
[6]  Hattori K, Yabe M, Matsumoto M, Kudo Y, Yasuda Y, Inoue H, et al. Successful hyperbaric oxygen treatment of life-threatening hemorrhagic cystitis after allogeneic bone marrow transplantation. Bone Marrow Transplantation. 2001; 27(12).View Article  PubMed 
 
[7]  Arnaout K, Patel N, Jain M, El-Amm J, Amro F, Tabbara IA. Complications of allogeneic hematopoietic stem cell transplantation. Cancer investigation. 2014; 32(7): 349-62.View Article  PubMed 
 
[8]  Srivastava A, Nair S, Srivastava V, Balamurugan A, Jeyaseelan L, Chandy M, et al. Evaluation of uroprotective efficacy of amifostine against cyclophosphamide induced hemorrhagic cystitis. Bone marrow transplantation. 1999; 23(5): 463-7.View Article  PubMed 
 
[9]  Ringdén O, Uzunel M, Rasmusson I, Remberger M, Sundberg B, Lönnies H, et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation. 2006; 81(10): 1390-7.View Article  PubMed 
 
[10]  Ordemann R, Naumann R, Geissler G, Bornhauser M, Schuler U, Ehninger G. Encouraging results in the treatment of haemorrhagic cystitis with estrogen-report of 10 cases and review of the literature. Bone marrow transplantation. 2000; 25(9): 981-5.13.View Article 
 
[11]  Pitto CM, Garcia-Perdomo HA. Interventions to treat hemorrhagic cystitis: a systematic review and meta-analysis. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. 2017; 25(7): 2043-6.View Article  PubMed 
 
[12]  Bevers R, Kurth K, Bakker D. Hyperbaric oxygen treatment for haemorrhagic radiation cystitis. The Lancet. 1995; 346(8978): 803-5.View Article 
 
[13]  El-Zimaity M, Saliba R, Chan K, Shahjahan M, Carrasco A, Khorshid O, et al. Hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: donor type matters. Blood. 2004; 103(12): 4674-80.View Article  PubMed 
 
[14]  Dellis A, Deliveliotis C, Kalentzos V, Vavasis P, Skolarikos A. Is there a role for hyberbaric oxygen as primary treatment for grade IV radiation-induced haemorrhagic cystitis? A prospective pilot-feasibility study and review of literature. International braz j urol. 2014; 40(3): 296-305.View Article  PubMed 
 
[15]  Shao Y, Lu Gl, Shen Zj. Comparison of intravesical hyaluronic acid instillation and hyperbaric oxygen in the treatment of radiation-induced hemorrhagic cystitis. BJU international. 2012; 109(5): 691-4.View Article  PubMed