Figure 3. β–hydroxybutyrate (ketone body) is oxidized into acetoacetate (another ketone body) that is later converted into acetyl CoA. Dichloroacetate is a structural analog and a proved inhibitor of oxidation of both ketone bodies. This supports my view that dichloroacetate is an inhibitor of ketone bodies oxidation (ketolysis)

From

Dichloroacetate is Promising for Treating Hematological Malignancy through Inhibiting Ketone Bodies Oxidation: towards Better Understanding of Its Anticancer Mechanisms

Mongi Ayat

American Journal of Cancer Prevention. 2018, 6(1), 5-8 doi:10.12691/ajcp-6-1-2