1Department of Clinical Biochemistry, Chalmeda Anandrao Institute of Medical Sciences, Karimnagar, Telangana, India
2Department of Clinical Microbiology, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India
3Department of Biochemistry, Vydehi Institute of Medical Sciences and Research Centre, #82, EPIP Area, Nallurhalli, Whitefield, Bangalore – 560066, Karnataka, India
4Department of Biotechnology, Vaagdevi Degree and PG College, Warangal, Telangana, India
Diabetes mellitus is a chronic debilitating non-communicable disease prevalent throughout the world. There are two different types of diabetes; the type 1 diabetes usually presents in children and young adults, and the type 2 diabetes, a most frequent age-related condition usually noted among the adults aged over 40 years. The type 1 diabetes results due to an immunological reaction against insulin and the insulin secreting cells. The type 2 diabetes can occur due to various factors that include genetic predisposition, lifestyle disorders, insulin resistance, and lack of adequate insulin production. Since lifestyle management is an adjustable risk factor for diabetes, may people with genetic predisposition could delay the onset of clinical diabetes. Further there is an increasing need to understand the genetics behind the signaling pathways involved in the development of type 2 diabetes, which could pave the way for formulating, and implementing therapeutic, and preventive strategies.
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